S-8599 Sorafenib, Free Base, >99%

Synonyms : [Bay 43-9006]

Related Terms : [Nexavar]

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  • 500 mg
  • 36
  • 33
  • 28
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  • 1 g
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  • 38
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  • 2 g
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  • 56
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  • 5 g
  • 155
  • 144
  • 121
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  • 10 g
  • 260
  • 242
  • 204
  • 41,100
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  • M.W. 464.82
  • C21H16ClF3N4O3
  • [284461-73-0]
  • M.I. 14: 8720

Storage: Store at or below -20 ºC. Solubility: Soluble in DMSO at 200 mg/mL; soluble in ethanol at 3.3 mg/mL with warming; very poorly soluble in water; maximum solubility in plain water is estimated to be about 10-50 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility. Disposal: A.

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  • More than 1,000 labs worldwide have purchased Sorafenib or its salt forms from LC Labs (either directly from us or from our many distributors, many of whom resell under their own labels).
  • This is the free base form of sorafenib; please see our product Sorafenib, p-Toluenesulfonate Salt, Cat. No. S-8502, for further technical information. It is the p-toluenesulfonate salt form, not the free base, that is used in the formulation of sorafenib for in vivo use.
  • Sorafenib (as the tosylate) is the active ingredient in the drug sold under the trade name Nexavar®. This drug has been approved in at least one country for use in patients with advanced renal cell cancer. NOTE: THE SORAFENIB SOLD BY LC LABORATORIES FOR RESEARCH IS NOT NEXAVAR®, AND IS NOT FOR HUMAN USE.
  • Sold for laboratory or manufacturing purposes only; not for human, vetrinary, food, or household use.
  • This product is offered for R&D use in accordance with (i) 35 USC 271(e)+A13(1) in the U.S.; (ii) Section 69.1 of Japanese Patent Law in Japan; (iii) Section 11, No. 2 of the German Patent Act of 1981 in Germany; (iv) Section 60, Paragraph 5b of the U.K. Patents Act of 1977 in the U.K.; (v) Sections 55.2(1) and 55.2(6) and other common law exemptions of Canadian patent law; (vi) Section 68B of the Patents Act of 1953 in New Zealand together with the amendment of same by the Statutes Amendment Bill of 2002; (vii) such related legislation and/or case law as may be or become applicable in the aforementioned countries; and (viii) such similar laws and rules as may apply in various other countries.
  • Not available in some countries; not available to some institutions; not available for some uses.