Tuesday 16 August 2022 - 03:15
PLEASE NOTE: During August 2022 we are doing a comprehensive revision of our customer service workflow. This includes training of current and new personnel. We are expecting that these changes will have only very minimal effects on our overall order processing and shipping activities. However, we do ask any customers who prefer that their shipments go out on Fridays to contact our Customer Service group and let them know about your preferences in advance. Thank you.
Reminder: Genuine LC Laboratories® brand PMA, which we have been manufacturing in the U.S. for more
than 40 years, is available directly from us: Cat No. P-1680 Phorbol 12-Myristate 13-Acetate, >99.5%.
Our PMA is also available from our >50 U.S. and international distributors, and from more than a dozen
major biochemical reagent "resellers" (who sell our PMA under their own brand names and labels)
FREE SHIPPING TO THE U.S. AND 32 OTHER COUNTRIES! [Read more].
G-1111 GW7647, Free Acid, >99%

- Size
- US $
- €
- £
- ¥
- 1 mg
- 35
- 34
- 28
- 4,600
- In stock
- 5 mg
- 49
- 48
- 40
- 6,500
- In stock
- 10 mg
- 79
- 77
- 65
- 10,500
- In stock
- 25 mg
- 146
- 143
- 120
- 19,400
- In stock
- 50 mg
- 259
- 253
- 214
- 34,400
- In stock
- 100 mg
- 374
- 366
- 309
- 49,600
- In stock
Note: Our Euro, Pound, and Yen prices are revised regularly to account for currency exchange rate fluctuations.
- M.W. 502.75
- C29H46N2O3S
- [265129-71-3]
Solubility: DMSO.
- GW7647 is a peroxisome proliferator-activated receptor-alpha (PPAR-alpha) agonist. A synergistic antinociceptive interaction between the endogenous cannabinoid receptor agonist anandamide and GW7647 was demonstrated in a model of acute chemical-induced pain. Russo R., et al. "Synergistic antinociception by the cannabinoid receptor agonist anandamide and the PPAR-alpha receptor agonist GW7647." Eur. J. Pharmacol. 566(1-3): 117-119 (2007).
- GW7647 promoted cholesterol efflux and ATP binding cassette transporter A1/G1 expression in primary macrophages. Nakaya K., et al. "Peroxisome proliferator-activated receptor-α activation promotes macrophage reverse cholesterol transport through a liver X receptor-dependent pathway." Arterioscler. Thromb. Vasc. Biol. 31(6): 1276-1282 (2011).
- GW7647 increased the production of high-density lipoprotein and decreased cholesterol esterification in Caco-2/TC7 cells. Colin S., et al. "Activation of intestinal peroxisome proliferator-activated receptor-α increases high-density lipoprotein production." Eur. Heart J. 34(32): 2566-2574 (2013).
- Sold for laboratory or manufacturing purposes only; not for human, veterinary, food, or household use.
- This product is offered for R&D use in accordance with (i) 35 USC 271(e)+A13(1) in the U.S.; (ii) Section 69.1 of Japanese Patent Law in Japan; (iii) Section 11, No. 2 of the German Patent Act of 1981 in Germany; (iv) Section 60, Paragraph 5b of the U.K. Patents Act of 1977 in the U.K.; (v) Sections 55.2(1) and 55.2(6) and other common law exemptions of Canadian patent law; (vi) Section 68B of the Patents Act of 1953 in New Zealand together with the amendment of same by the Statutes Amendment Bill of 2002; (vii) such related legislation and/or case law as may be or become applicable in the aforementioned countries; and (viii) such similar laws and rules as may apply in various other countries.
- Not available in some countries; not available to some institutions; not available for some uses.
