Tuesday 16 August 2022 - 02:51
In Business 42 Years - Since 1980
PLEASE NOTE: During August 2022 we are doing a comprehensive revision of our customer service workflow. This includes training of current and new personnel. We are expecting that these changes will have only very minimal effects on our overall order processing and shipping activities. However, we do ask any customers who prefer that their shipments go out on Fridays to contact our Customer Service group and let them know about your preferences in advance. Thank you.
Reminder: Genuine LC Laboratories® brand PMA, which we have been manufacturing in the U.S. for more
than 40 years, is available directly from us: Cat No. P-1680 Phorbol 12-Myristate 13-Acetate, >99.5%.
Our PMA is also available from our >50 U.S. and international distributors, and from more than a dozen
major biochemical reagent "resellers" (who sell our PMA under their own brand names and labels)
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B-1709 Bosutinib--Explanation of the Problem and Bosutinib Isomer 1, 99%
- Size
- US $
- €
- £
- ¥
Note: Our Euro, Pound, and Yen prices are revised regularly to account for currency exchange rate fluctuations.
- M.W. 530.45
- C26H29Cl2N5O3
- Bosutinib (SKI-606) is a tyrosine kinase inhibitor, more potent than imatinib.
- Aside from the ongoing clinical studies, bosutinib is also used extensively in biomedical research laboratories around the world, for non-human, non-veterinary studies.
- Very unfortunately, an incorrect isomer of bosutinib has been sold to laboratory researchers under the name "Bosutinib" by 17 vendors, for various periods as long as several years. For extensive information about this bosutinib problem, please visit http://www.pkcpharma.com/TwoOrMoreBosutinibs.html.
- LC Laboratories is one of the 17 vendors that sold the incorrect bosutinib isomer under the name "Bosutinib", and the corresponding catalog number was B-1709.
- To avoid confusion, we have permanently discontinued use of the B-1709 catalog number. All of the incorrect bosutinb isomer sold by LC Labs at any time was sold under the catalog number "B-1709" and name "Bosutinib, Free Base".
- We have now produced our own correct bosutinib and unambiguously proven its structure by X-ray crystallography. We have assigned a new catalog number, B-1788, to this correct bosutinib product. Please see that product page for extensive information, sizes and prices -- Cat. No. B-1788, Bosutinib, Free Base
- We now refer to the particular incorrect bosutinib isomer erroneously sold by the 17 vendors as "Bosutinib Isomer 1".
- We have obtained unambiguous proof of the structure of Bosutinib Isomer 1 via X-ray crystallography, and we now offer this compound for sale under catalog number B-1722. Please see that product page for further information, sizes and prices -- Cat. No. B-1722, Bosutinib Isomer 1, Free Base
- An 18th vendor has also sold incorrect bosutinib, specifically to the laboratory headed by Prof. Stefan Knapp. The incorrect version of bosutinib sold by this vendor has been unambiguously proven to be different from bosutinib but its actual structure has not yet been established.
