R-8765 Resiniferonol 9,13,14-Orthophenylacetate, >99%

Related Terms : [ROPA]

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  • 1 mg
  • 39
  • 35
  • 29
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  • In stock
  • 5 mg
  • 127
  • 115
  • 96
  • 13,500
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  • 10 mg
  • 239
  • 217
  • 182
  • 25,400
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  • 25 mg
  • 515
  • 467
  • 392
  • 54,700
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  • 100 mg
  • 1,675
  • 1,520
  • 1,276
  • 177,900
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  • Out of stock

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  • M.W. 464.55
  • C28H32O6
  • [57852-42-3]

Warnings: Highly irritant to skin and mucous membranes. SPECIAL HAZARD: TUMOR PROMOTER. Gloves and mask should be worn when using this compound. Care must be taken to prevent contact through all routes of exposure.

Storage: Store at or below -20 ºC. Solubility: Soluble in DMSO or ethanol. Disposal: A.

  • 20-Deacylated derivative of resiniferatoxin and tinyatoxin. Not active as a capsaicin analog.
  • Binds to and activates protein kinase C with high potency. Geiges, D., et al. "Activation of protein kinase C subtypes alpha, gamma, delta, epsilon, zeta, and eta by tumor-promoting and nontumor-promoting agents." Biochem Pharmacol. 53: 865-875 (1997).
  • Useful as starting material for synthesis of resiniferatoxin analogs.
  • Please request Technical Note #28 for additional information.
  • Sold for laboratory or manufacturing purposes only; not for human, medical, veterinary, food, or household use.
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