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Biological Activity Index
Adenylate Cyclase
Activators
F-9929 Forskolin
Apoptosis Reagents
Alcohol Dehydrogenase Inhibitors
ATPase Inhibitors (See Also Ion-Modulating
Reagents—Ion Co-Transporters)
Calcineurin (See Protein Phosphatase 2B)
Calcium-Related Reagents
Calcium Releasers (from Intracellular Stores)
T-3250 ThapsigarginIon Channel Activators
Calcium/Divalent Cation Channel Activators
I-6400 5'-Iodoresiniferatoxin (5'-IRTX)
I-2000 6'-Iodoresiniferatoxin (6'-IRTX)
P-6388 PPAHV (Phorbol 12-Phenylacetate 13-Acetate 20-Homovanillate)
R-6712 Resiniferatoxin (RTX)
T-5096 Tinyatoxin (TYX)TRPV Cation Channel Activators (a.k.a. OTRPCH, VR-OAC, TRP12, VRL-2)
P-1571 4α-Phorbol 12,13-Diacetate
P-4678 4α-Phorbol 12,13-Dibutyrate
P-2170 4α-Phorbol 12,13-Didecanoate
P-8880 4α-Phorbol 12-Myristate 13-Acetate
Ionophores, Calcium
I-5700 Ionomycin, Free Acid
I-6800 Ionomycin, Calcium SaltIon Transporter/Co-transporter Inhibitors (Ca2+)
T-3250 Thapsigargin
Capsaicin-Related Reagents
I-6400 5'-Iodoresiniferatoxin (5'-IRTX)
I-2000 6'-Iodoresiniferatoxin (6'-IRTX)
P-6388 PPAHV (Phorbol 12-Phenylacetate 13-Acetate 20-Homovanillate)
R-6712 Resiniferatoxin (RTX)
T-5096 Tinyatoxin (TYX)
cdc/cdk Kinases (See Cell Cycle Reagents)
Cell Cycle Reagents
Cyclin/cdc/cdk Kinases
Inhibitors
R-1234 Roscovitine
CSBP Kinase (See MEK and MEK Kinases)
Cyclic Nucleotide Reagents
See individual entries, e.g. Adenylate Cyclase,
Guanylate Cyclase, Phosphodiesterase, PKA, PKC, PKG
Cyclin/cdc/cdk Kinases (See Cell Cycle Reagents)
EGF Receptor Kinase Inhibitors (See also Tyrosine Kinase Reagents)
T-7310 Tyrphostin AG 1478
T-3655 Tyrphostin AG 1478, Methanesulfonate Salt
Endoplasmic Reticulum Reagents
Enzyme Activators and Inhibitors — See individual enzyme entries
ERK Kinase (See MEK and MEK Kinases)
FLK-1 (See VEGF Receptor Kinase)
Golgi Reagents
B-8500 Brefeldin A
Heat Shock Protein Modulators
A-6880 17-AAG
D-3440 17-DMAG, Hydrochloride Salt
G-4500 Geldanamycin
Hedgehog Inhibitors
C-8700 Cyclopamine
Histamine Secretagogues
T-3250 Thapsigargin
Immunosuppressants
C-6000 Cyclosporin A
E-4040 Everolimus
F-4900 FK-506
P-6040 Pimecrolimus
R-5000 Rapamycin
T-8040 Temsirolimus
Z-9040 Zotarolimus
Ion-Modulating Reagents
H+-ATPase Inhibitors (See also ATPase Inhibitors)
B-1080 Bafilomycin A1Calcium Releasers (from Intracellular Stores)
T-3250 ThapsigarginIon Channel Activators
Calcium/Divalent Cation Channel Activators
I-6400 5'-Iodoresiniferatoxin (5'-IRTX)
I-2000 6'-Iodoresiniferatoxin (6'-IRTX)
P-6388 PPAHV (Phorbol 12-Phenylacetate 13-Acetate 20-Homovanillate)
R-6712 Resiniferatoxin (RTX)
T-5096 Tinyatoxin (TYX)TRPV Cation Channel Activators (a.k.a. OTRPCH, VR-OAC, TRP12, VRL-2)
P-1571 4α-Phorbol 12,13-Diacetate
P-4678 4α-Phorbol 12,13-Dibutyrate
P-2170 4α-Phorbol 12,13-Didecanoate
P-8880 4α-Phorbol 12-Myristate 13-Acetate
Ionophores, Calcium
I-5700 Ionomycin, Free Acid
I-6800 Ionomycin, Calcium SaltIon Transporter/Co-transporter Inhibitors (Ca2+)
T-3250 Thapsigargin
Isoflavones (See Soybean Isoflavones)
JAK-2 Kinase Inhibitors
T-9142 Tyrphostin AG 490
Kinase Inhibitors, Non-Selective
MAP Kinases (See MEK and MEK Kinases)
MEK and MEK Kinases
Inhibitors
D-2744 Doramapimod
P-4313 PD 98059
S-1700 SB 202190
S-3400 SB 203580
U-6770 U0126
Myosin Light Chain Kinase Reagents
Inhibitors
W-2990 Wortmannin
Neurochemicals
I-6400 5'-Iodoresiniferatoxin (5'-IRTX)
I-2000 6'-Iodoresiniferatoxin (6'-IRTX)
P-6388 PPAHV (Phorbol 12-Phenylacetate 13-Acetate 20-Homovanillate)
R-6712 Resiniferatoxin (RTX)
T-5096 Tinyatoxin (TYX)
Nuclear Export Inhibitors
L-6100 Leptomycin B (LMB)
p38 Kinase (See MEK and MEK Kinases)
p40 Kinase (See MEK and MEK Kinases)
Phosphatidylinositol 3-Kinase Inhibitors
PI3-Kinase (See Phosphatidylinositol 3-Kinase Inhibitors)
Proteasome Inhibitors
B-1408 Bortezomib
Protein Kinase A (PKA)
PKA Inhibitors
F-4660 Fasudil, Monohydrochloride Salt
H-5239 H-89, Dihydrochloride Salt
H-2330 HA-1077, Dihydrochloride Salt
K-9609 K252c
S-9300 Staurosporine
Protein Kinase C (PKC)
PKC Activators
PKC-selective but not PKC Isotype-selective Activators
B-6697 Bryostatin 1
B-3517 Bryostatin 2
I-8560 Ingenol
M-2550 4-O-Methylphorbol 12-Myristate 13-Acetate
P-4227 Phorbol 13-Acetate
P-7350 Phorbol 13-Decanoate
P-5005 Phorbol 12,13-Diacetate
P-3106 Phorbol 12,13-Dibenzoate
P-4833 Phorbol 12,13-Dibutyrate
P-1925 Phorbol 12,13-Didecanoate
P-3814 Phorbol 12,13-Dihexanoate
P-1680 Phorbol 12-Myristate 13-Acetate
P-4462 Prostratin
R-8765 Resiniferonol 9,13,14-OrthophenylacetateNegative Controls
P-1571 4α-Phorbol 12,13-Diacetate
P-4678 4α-Phorbol 12,13-Dibutyrate
P-2170 4α-Phorbol 12,13-Didecanoate
P-8880 4α-Phorbol 12-Myristate 13-AcetatePKC Inhibitors
PKC-selective but not PKC Isotype-selective Inhibitors
B-2464 Bisindolylmaleimide I
B-6191 Bisindolylmaleimide I, Hydrochloride Salt
B-7334 Bisindolylmaleimide IX, Methanesulfonate Salt
B-7204 Bisindolylmaleimide X, Hydrochloride Salt
B-8777 Bisindolylmaleimide XI, Hydrochloride Salt
C-3030 Chelerythrine ChloridePKC Isotype-selective Inhibitors
G-6203 Gö 6976
R-9630 Rottlerin - SEE IMPORTANT NOTE!!PKC Inhibitors not Selective for PKC or of Unknown Selectivity
H-5239 H-89, Dihydrochloride Salt
K-9609 K252c
P-7600 PKC412
S-9300 Staurosporine
Protein Kinase G (PKG)
PKG Inhibitors
F-4660 Fasudil, Monohydrochloride Salt
H-2330 HA-1077, Dihydrochloride Salt
S-9300 Staurosporine
Protein Kinase Inhibitors (see also individual enzymes)
Inhibitors
B-2464 Bisindolylmaleimide I
B-6191 Bisindolylmaleimide I, Hydrochloride Salt
B-7334 Bisindolylmaleimide IX, Methanesulfonate Salt
B-7204 Bisindolylmaleimide X, Hydrochloride Salt
B-8777 Bisindolylmaleimide XI, Hydrochloride Salt
C-3030 Chelerythrine Chloride
D-3307 Dasatinib
E-4007 Erlotinib, Hydrochloride Salt
F-4660 Fasudil, Monohydrochloride Salt
G-4408 Gefitinib
G-6055 Genistein
G-6203 Gö 6976
H-5239 H-89, Dihydrochloride Salt
H-2330 HA-1077, Dihydrochloride Salt
I-5508 Imatinib, Methanesulfonate Salt
K-9609 K252c
L-4804 Lapatinib, Di-p-Toluenesulfonate Salt
L-6307 Lestaurtinib
L-7962 LY 294002
N-8207 Nilotinib
O-5679 OSU-03012, Hydrochloride Salt
P-4313 PD98059
P-7600 PKC412
R-1234 Roscovitine
S-1700 SB 202190
S-3400 SB 203580
S-8502 Sorafenib, p-Toluenesulfonate Salt
S-7979 SP600125
S-9300 Staurosporine
S-8803 Sunitinib, Malate Salt
T-9142 Tyrphostin AG 490
T-7310 Tyrphostin AG 1478
T-3655 Tyrphostin AG 1478, Methanesulfonate Salt
T-2710 Tyrphostin SU 1498
U-6770 U0126
V-9402 Vandetanib
V-8303 Vatalanib, Dihydrochloride Salt
W-2990 Wortmannin
Protein Phosphatase 1 Reagents
Inhibitors
C-3987 Calyculin A
O-2220 Okadaic Acid
O-6410 Okadaic Acid, Ammonium Salt
O-7519 Okadaic Acid, Potassium Salt
O-5857 Okadaic Acid, Sodium Salt
Protein Phosphatase 2A Reagents
Inhibitors
C-3987 Calyculin A
O-2220 Okadaic Acid
O-6410 Okadaic Acid, Ammonium Salt
O-7519 Okadaic Acid, Potassium Salt
O-5857 Okadaic Acid, Sodium Salt
Protein Phosphatase 2B (Calcineurin) Reagents
Inhibitors
C-6000 Cyclosporin ARelated Reagents
E-4040 Everolimus
F-4900 FK-506
P-6040 Pimecrolimus
R-5000 Rapamycin
T-8040 Temsirolimus
Z-9040 Zotarolimus
Protein Trafficking Reagents
B-8500 Cyclosporin A
Rho-Associated Kinase II
Inhibitors
F-4660 Fasudil, Monohydrochloride Salt
H-2330 HA-1077, Dihydrochloride Salt
RK Kinase (See MEK and MEK Kinases)
Smoothened (Smo) Inhibitors
C-8700 Cyclopamine
Soybean Isoflavone-Related Compounds
Soybean Constituents
A-6900 6"-O-Acetyldaidzin
A-3000 6"-O-Acetylgenistin
A-7860 6"-O-Acetylglycitin
D-2946 Daidzein
D-7878 Daidzin
G-6055 Genistein
G-5200 Genistin
G-1152 Glycitein
G-2822 Glycitin
M-6730 6"-O-Malonyldaidzin
M-8090 6"-O-Malonylgenistin
M-4620 6"-O-MalonylglycitinSoybean Isoflavone Metabolites
D-9200 (R,S)-2,3-Dihydrodaidzein
E-5880 (R,S)-Equol
TRPV Cation Channel Activators (a.k.a. OTRPCH, VR-OAC, TRP12, VRL-2)
P-1571 4α-Phorbol 12,13-Diacetate
P-4678 4α-Phorbol 12,13-Dibutyrate
P-2170 4α-Phorbol 12,13-Didecanoate
P-8880 4α-Phorbol 12-Myristate 13-Acetate
Tubulin Assembly/Stabilization Promoters
VEGF Receptor Kinase Inhibitor
T-2710 Tyrphostin SU 1498
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