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In Business 32 Years - Since 1980 |
THE CURRENT TIME at LC Labs is: |
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[4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole]
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Size |
US $ |
€ |
£ |
¥ |
|
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|
25 mg |
69 |
52 |
44 |
5300 |
| ||
|
50 mg |
105 |
80 |
66 |
8000 |
| ||
|
100 mg |
164 |
125 |
104 |
12600 |
| ||
|
200 mg |
277 |
210 |
175 |
21200 |
| ||
|
500 mg |
615 |
467 |
389 |
47100 |
| ||
|
1 g |
1095 |
832 |
692 |
83900 |
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Note: Our Euro, Pound, and Yen prices are revised regularly to account for currency exchange rate fluctuations.
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M.W. 377.43
C21H16FN3OS
[152121-47-6]
Storage: Store at or below -20 ºC. Solubility: Soluble in DMSO at 100 mg/mL; soluble in ethanol at 12.5 mg/mL with warming; very poorly soluble in water; maximum solubility in plain water is estimated to be about 10-50 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility. Appearance: white to off-white solid. Disposal: A
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View the MSDS for this product
Important, highly specific inhibitor of the kinase known variously as p38, p40, CSBP, or RK. This kinase is a homolog of MAP kinase. Gallagher, T.F., et al. "2,4,5-Triarylimidazole inhibitors of Il-1 biosynthesis." Bioorg. Med. Chem. Lett. 5: 1171-1176 (1995). Cuenda, A., et al. "SB203580 is a specific inhibitor of MAP kinase homologue which is stimulated by cellular stresses and interleukin-1." FEBS Lett.. 364: 229-233 (1995). Hazzalin, C.A., et al. "Effects of the inhibition of p38/RK MAP kinase on induction of five fos and jun genes by diverse stimuli." Oncogene 15: 2321-2331 (1997).
Sold for laboratory or manufacturing purposes only; not for human, medical, veterinary, food, or household use.
Our products are for laboratory research only and are sold only to qualified research institutions, not to individuals or patients nor for veterinary use.