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[4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole]
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Size |
US $ |
€ |
£ |
¥ |
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5 mg |
49 |
41 |
27 |
5900 |
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|
10 mg |
77 |
64 |
42 |
9200 |
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25 mg |
143 |
119 |
79 |
17200 |
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100 mg |
499 |
414 |
274 |
59900 |
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250 mg |
1125 |
934 |
619 |
135000 |
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| US Dollars ($) | European Union Euros (€) | British Pounds (£) | Japanese Yen (¥) |
M.W. 377.44
C21H16FN3OS
[152121-47-6]
Storage: Store at or below -20 ºC. Solubility: Soluble in DMSO. Appearance: white to off-white solid. Disposal: A
View the MSDS for this product
Important, highly specific inhibitor of the kinase known variously as p38, p40, CSBP, or RK. This kinase is a homolog of MAP kinase. Gallagher, T.F., et al. "2,4,5-Triarylimidazole inhibitors of Il-1 biosynthesis." Bioorg. Med. Chem. Lett. 5: 1171-1176 (1995). Cuenda, A., et al. "SB203580 is a specific inhibitor of MAP kinase homologue which is stimulated by cellular stresses and interleukin-1." FEBS Lett.. 364: 229-233 (1995). Hazzalin, C.A., et al. "Effects of the inhibition of p38/RK MAP kinase on induction of five fos and jun genes by diverse stimuli." Oncogene 15: 2321-2331 (1997).
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