In Business 32 Years - Since 1980
THE CURRENT TIME at LC Labs is:
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In Business 32 Years - Since 1980 |
THE CURRENT TIME at LC Labs is: |
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[2'-Amino-3'-methoxyflavone]
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 |
 |
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Size |
US $ |
€ |
£ |
¥ |
|
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|
5 mg |
44 |
33 |
28 |
3400 |
| ||
|
10 mg |
62 |
47 |
39 |
4800 |
| ||
|
25 mg |
142 |
108 |
90 |
10900 |
| ||
|
50 mg |
235 |
179 |
149 |
18000 |
| ||
|
100 mg |
328 |
249 |
207 |
25100 |
| ||
|
200 mg |
508 |
386 |
321 |
38900 |
| ||
|
300 mg |
687 |
522 |
434 |
52700 |
| ||
|
1 g |
1690 |
1284 |
1068 |
129600 |
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Note: Our Euro, Pound, and Yen prices are revised regularly to account for currency exchange rate fluctuations.
| Compare Prices and Purity — LC Labs vs. Other Suppliers |
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M.W. 267.28
C16H13NO3
[167869-21-8]
Storage: Store at or below -20 ºC. Solubility: Soluble in DMSO at 25 mg/mL; soluble in ethanol at 1 mg/mL with warming; very poorly soluble in water; maximum solubility in plain water is estimated to be about 50-100 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility. Appearance: Pale-yellow powder Disposal: A
Find and View a Certificate of Analysis for this product
View the MSDS for this product
Potent, selective and cell-permeable inhibitor of MAP kinase kinase (also known as MAPK/ERK kinase or MEK kinase). Inhibits phosphorylation of MAP kinase by MAP kinase kinase. PD 98059 does not inhibit MAP kinase itself. IC50 values for PD 98059-induced effects are in the 1-20 µM range for many assays; it is somewhat weaker in inhibiting cell growth in monolayers or agar for some cell lines. Dudley, D.T., et al. "A synthetic inhibitor of the mitogen-activated protein kinase cascade." "Proc. Natl. Acad. Sci. USA 92: 7686-7689 (1995). Pang, L., et al. "Inhibition of MAP kinase kinase blocks the differentiation of PC-12 cells induced by nerve growth factor." J. Biol. Chem. 270: 13585-13588 (1995). Waters, S.B., et al. "Desensitization of Ras activation by a feedback disassociation of the SOS-Grb2 complex." J. Biol. Chem. 270: 20883-20886 (1995). Langlois, W.J., et al. "Negative feedback regulation and desensitization of insulin- and epidermal growth factor-stimulated p21ras activation." J. Biol. Chem. 270: 25320-25323 (1995). Alessi, D.R., et al. "PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo." J. Biol. Chem. 270: 27489-27494 (1995).
Sold for laboratory or manufacturing purposes only; not for human, medical, veterinary, food, or household use.
Our products are for laboratory research only and are sold only to qualified research institutions, not to individuals or patients nor for veterinary use.
